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Development of a Simple and Quick Method to Assess Base Editing in Human Cells

Base editing is a form of genome editing that can directly convert a single base (C or A) to another base (T or G), which is of great potential in biomedical applications. The broad application of base editing is limited by its low activity and specificity, which still needs to be resolved. To addre...

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Detalles Bibliográficos
Autores principales: Lv, Xiujuan, Qiu, Kairui, Tu, Tianxiang, He, Xiaoxue, Peng, Yuchen, Ye, Jinbin, Fu, Junhao, Deng, Ruzhi, Wang, Yuqin, Wu, Jinyu, Liu, Changbao, Zhao, Junzhao, Gu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184106/
https://www.ncbi.nlm.nih.gov/pubmed/32335475
http://dx.doi.org/10.1016/j.omtn.2020.03.004