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Time-dependent simvastatin administration enhances doxorubicin toxicity in neuroblastoma
Statins have a primary indication for the reduction and management of hypercholesterolemia; however, evidence shows that statins have the ability to increase the toxicity of chemotherapeutics within cancer cells by inducing anti-proliferative, anti-metastatic, and anti-angiogenic effects. More recen...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184108/ https://www.ncbi.nlm.nih.gov/pubmed/32368502 http://dx.doi.org/10.1016/j.toxrep.2020.03.007 |