Reversal of mcr-1-Mediated Colistin Resistance in Escherichia coli by CRISPR-Cas9 System

PURPOSE: The plasmid-borne mobilized colistin resistance gene (mcr-1) was discovered in 2015. Subsequently, the rapid horizontal transfer of mcr-1 gene to diverse bacterial species poses a serious threat to public health, which urgently needs the introduction of novel antimicrobial strategies. There...

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Detalles Bibliográficos
Autores principales: Wan, Peng, Cui, Shiyun, Ma, Zhenbao, Chen, Lin, Li, Xiaoshen, Zhao, Ruonan, Xiong, Wenguang, Zeng, Zhenling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184118/
https://www.ncbi.nlm.nih.gov/pubmed/32368108
http://dx.doi.org/10.2147/IDR.S244885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184118/
https://www.ncbi.nlm.nih.gov/pubmed/32368108
http://dx.doi.org/10.2147/IDR.S244885

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