Cargando…

Reversal of mcr-1-Mediated Colistin Resistance in Escherichia coli by CRISPR-Cas9 System

PURPOSE: The plasmid-borne mobilized colistin resistance gene (mcr-1) was discovered in 2015. Subsequently, the rapid horizontal transfer of mcr-1 gene to diverse bacterial species poses a serious threat to public health, which urgently needs the introduction of novel antimicrobial strategies. There...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wan, Peng, Cui, Shiyun, Ma, Zhenbao, Chen, Lin, Li, Xiaoshen, Zhao, Ruonan, Xiong, Wenguang, Zeng, Zhenling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184118/ https://www.ncbi.nlm.nih.gov/pubmed/32368108 http://dx.doi.org/10.2147/IDR.S244885

Ejemplares similares

Targeted Elimination of bla(NDM-5) Gene in Escherichia coli by Conjugative CRISPR-Cas9 System
por: Li, Peisi, et al.
Publicado: (2022)

Molecular epidemiology and transmission of rmtB-positive Escherichia coli among ducks and environment
por: Li, Guihua, et al.
Publicado: (2023)

Rapid Detection of MCR-Mediated Colistin Resistance in Escherichia coli
por: Zhang, Haijie, et al.
Publicado: (2022)

In vitro reduction of colistin susceptibility and comparative genomics reveals multiple differences between MCR-positive and MCR-negative colistin-resistant Escherichia coli
por: Luo, Qixia, et al.
Publicado: (2019)

Molecular Epidemiology and Colistin Resistant Mechanism of mcr-Positive and mcr-Negative Clinical Isolated Escherichia coli
por: Luo, Qixia, et al.
Publicado: (2017)

High Prevalence of Colistin Resistance and mcr-1 Gene in Escherichia coli Isolated from Food Animals in China
por: Huang, Xianhui, et al.
Publicado: (2017)

Novel Plasmid-Mediated Colistin Resistance Gene mcr-3 in Escherichia coli
por: Yin, Wenjuan, et al.
Publicado: (2017)

Identification of Functional Interactome of Colistin Resistance Protein MCR-1 in Escherichia coli
por: Li, Hui, et al.
Publicado: (2021)

Synergistic Activity of Tetrandrine and Colistin against mcr-1-Harboring Escherichia coli
por: Shafiq, Muhammad, et al.
Publicado: (2022)

Colistin exposure enhances expression of eptB in colistin-resistant Escherichia coli co-harboring mcr-1
por: Elizabeth, Rajkumari, et al.
Publicado: (2022)

Rapid Increase in the IS26-Mediated cfr Gene in E. coli Isolates with IncP and IncX4 Plasmids and Co-Existing cfr and mcr-1 Genes in a Swine Farm
por: Ma, Zhenbao, et al.
Publicado: (2021)

Pathogenic Lineage of mcr-Negative Colistin-Resistant Escherichia coli, Japan, 2008–2015
por: Sato, Toyotaka, et al.
Publicado: (2016)

ISEc69-Mediated Mobilization of the Colistin Resistance Gene mcr-2 in Escherichia coli
por: He, Yu-Zhang, et al.
Publicado: (2021)

Occurrence of mcr-1 and mcr-2 colistin resistance genes in porcine Escherichia coli isolates (2010–2020) and genomic characterization of mcr-2-positive E. coli
por: Ewers, Christa, et al.
Publicado: (2022)

A Transposon-Associated CRISPR/Cas9 System Specifically Eliminates both Chromosomal and Plasmid-Borne mcr-1 in Escherichia coli
por: He, Yu-Zhang, et al.
Publicado: (2021)

Screening for fecal presence of colistin-resistant Escherichia coli and mcr-1 and mcr-2 genes in camel-calves in southern Tunisia
por: Rhouma, Mohamed, et al.
Publicado: (2018)

Crystal Structure of Escherichia coli originated MCR-1, a phosphoethanolamine transferase for Colistin Resistance
por: Hu, Menglong, et al.
Publicado: (2016)

Colistin-Resistant mcr-1–Positive Pathogenic Escherichia coli in Swine, Japan, 2007−2014
por: Kusumoto, Masahiro, et al.
Publicado: (2016)

Colistin Resistance mcr-1-Gene-Bearing Escherichia coli Strain from the United States
por: Meinersmann, Richard J., et al.
Publicado: (2016)

mcr-1–Positive Colistin-Resistant Escherichia coli in Traveler Returning to Canada from China
por: Payne, Michael, et al.
Publicado: (2016)

Colistin resistant Escherichia coli carrying mcr-1 in urban sludge samples: Dhaka, Bangladesh
por: Islam, Aminul, et al.
Publicado: (2017)

Discovery of mcr-1-Mediated Colistin Resistance in a Highly Virulent Escherichia coli Lineage
por: Forde, Brian M., et al.
Publicado: (2018)

Colistin-resistant Escherichia coli with mcr genes in the livestock of rural small-scale farms in Ecuador
por: Yamamoto, Yoshimasa, et al.
Publicado: (2019)

Quantitative Release Assessment of mcr-mediated Colistin-resistant Escherichia Coli from Japanese Pigs
por: Makita, Kohei, et al.
Publicado: (2020)

Impact of mcr-1 on the Development of High Level Colistin Resistance in Klebsiella pneumoniae and Escherichia coli
por: Zhu, Xiao-Qing, et al.
Publicado: (2021)

Colistin Resistance and Molecular Characterization of the Genomes of mcr-1-Positive Escherichia coli Clinical Isolates
por: Li, Qiaoling, et al.
Publicado: (2022)

Escherichia coli B-Strains Are Intrinsically Resistant to Colistin and Not Suitable for Characterization and Identification of mcr Genes
por: Schumann, Anna, et al.
Publicado: (2023)

CRISPR/Cas Technologies and Their Applications in Escherichia coli
por: Dong, Huina, et al.
Publicado: (2021)

Molecular survey of mcr1 and mcr2 plasmid mediated colistin resistance genes in Escherichia coli isolates of animal origin in Iran
por: Ilbeigi, Kayhan, et al.
Publicado: (2021)

Molecular Epidemiology and Colistin-Resistant Mechanism of mcr-Positive and mcr-Negative Escherichia coli Isolated From Animal in Sichuan Province, China
por: Li, Fulei, et al.
Publicado: (2022)

Effect of Different Media on the Bactericidal Activity of Colistin and on the Synergistic Combination With Azidothymidine Against mcr-1-Positive Colistin-Resistant Escherichia coli
por: Loose, Maria, et al.
Publicado: (2020)

CRISPR-Cas adaptation in Escherichia coli
por: Mitić, Damjan, et al.
Publicado: (2023)

High Prevalence of Colistin-Resistant Escherichia coli with Chromosomally Carried mcr-1 in Healthy Residents in Vietnam
por: Yamaguchi, Takahiro, et al.
Publicado: (2020)

Genomic Insights into the Colistin Resistant mcr-Carrying Escherichia coli Strains in a Tertiary Hospital in China
por: Li, Guoli, et al.
Publicado: (2022)

Genome sequences of two clinical Escherichia coli isolates harboring the novel colistin-resistance gene variants mcr-1.26 and mcr-1.27
por: Neumann, Bernd, et al.
Publicado: (2020)

Occurrence of the mobile colistin resistance gene mcr-3 in Escherichia coli from household pigs in rural areas
por: Li, Jiyun, et al.
Publicado: (2018)

Erratum for Yin et al., “Novel Plasmid-Mediated Colistin Resistance Gene mcr-3 in Escherichia coli”
por: Yin, Wenjuan, et al.
Publicado: (2017)

High prevalence of mcr-1-encoded colistin resistance in commensal Escherichia coli from broiler chicken in Bangladesh
por: Ahmed, Shahana, et al.
Publicado: (2020)

MCR-1 Gene Encoded Colistin-Resistant Escherichia coli in Raw Chicken Meat and Bean Sprouts in Malaysia
por: Aklilu, Erkihun, et al.
Publicado: (2020)

Characteristics of a Colistin-Resistant Escherichia coli ST695 Harboring the Chromosomally-Encoded mcr-1 Gene
por: Peng, Zhong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_104qmhima3g536r7nulopsqmuh