Functional changes of the liver in the absence of growth hormone (GH) action – Proteomic and metabolomic insights from a GH receptor deficient pig model

OBJECTIVE: The liver is a central target organ of growth hormone (GH), which stimulates the synthesis of insulin-like growth factor 1 (IGF1) and affects multiple biochemical pathways. A systematic multi-omics analysis of GH effects in the liver has not been performed. GH receptor (GHR) deficiency is...

Descripción completa

Detalles Bibliográficos
Autores principales: Riedel, Evamaria O., Hinrichs, Arne, Kemter, Elisabeth, Dahlhoff, Maik, Backman, Mattias, Rathkolb, Birgit, Prehn, Cornelia, Adamski, Jerzy, Renner, Simone, Blutke, Andreas, de Angelis, Martin Hrabĕ, Bidlingmaier, Martin, Schopohl, Jochen, Arnold, Georg J., Fröhlich, Thomas, Wolf, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184181/
https://www.ncbi.nlm.nih.gov/pubmed/32277923
http://dx.doi.org/10.1016/j.molmet.2020.100978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184181/
https://www.ncbi.nlm.nih.gov/pubmed/32277923
http://dx.doi.org/10.1016/j.molmet.2020.100978

Ejemplares similares