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CD41-deficient exosomes from non-traumatic femoral head necrosis tissues impair osteogenic differentiation and migration of mesenchymal stem cells

Non-traumatic osteonecrosis of the femoral head (ONFH) is clinically a devastating and progressive disease without an effective treatment. Mesenchymal stem cells (MSCs) transplantation has been used to treat ONFH in early stage, but the failure rate of this therapy is high due to the reduced osteoge...

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Detalles Bibliográficos
Autores principales: Zhu, Weiwen, Guo, MinKang, Yang, Wu, Tang, Min, Chen, Tingmei, Gan, Delu, Zhang, Dian, Ding, Xiaojuan, Zhao, Anping, Zhao, Pei, Yan, Wenlong, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184624/
https://www.ncbi.nlm.nih.gov/pubmed/32341357
http://dx.doi.org/10.1038/s41419-020-2496-y