Analyzing the impact of Mycobacterium tuberculosis infection on primary human macrophages by combined exploratory and targeted metabolomics

The pathogenic success of Mycobacterium tuberculosis (Mtb) is tightly linked to its ability to recalibrate host metabolic processes in infected host macrophages. Since changes in cellular metabolic intermediates or pathways also affect macrophage function in response to pathogens, we sought to analy...

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Detalles Bibliográficos
Autores principales: Vrieling, Frank, Kostidis, Sarantos, Spaink, Herman P., Haks, Mariëlle C., Mayboroda, Oleg A., Ottenhoff, Tom H. M., Joosten, Simone A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184630/
https://www.ncbi.nlm.nih.gov/pubmed/32341411
http://dx.doi.org/10.1038/s41598-020-62911-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184630/
https://www.ncbi.nlm.nih.gov/pubmed/32341411
http://dx.doi.org/10.1038/s41598-020-62911-1

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