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Intra-CSF AAV9 and AAVrh10 Administration in Nonhuman Primates: Promising Routes and Vectors for Which Neurological Diseases?

The identification of the most efficient method for whole central nervous system targeting that is translatable to humans and the safest route of adeno-associated virus (AAV) administration is a major concern for future applications in clinics. Additionally, as many AAV serotypes were identified for...

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Detalles Bibliográficos
Autores principales: Bey, Karim, Deniaud, Johan, Dubreil, Laurence, Joussemet, Béatrice, Cristini, Joseph, Ciron, Carine, Hordeaux, Juliette, Le Boulc’h, Morwenn, Marche, Kevin, Maquigneau, Maud, Guilbaud, Michaël, Moreau, Rosalie, Larcher, Thibaut, Deschamps, Jack-Yves, Fusellier, Marion, Blouin, Véronique, Sevin, Caroline, Cartier, Nathalie, Adjali, Oumeya, Aubourg, Patrick, Moullier, Philippe, Colle, Marie-Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184633/
https://www.ncbi.nlm.nih.gov/pubmed/32355866
http://dx.doi.org/10.1016/j.omtm.2020.04.001