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Identifying transglutaminase reaction products via mass spectrometry as exemplified by the MUC2 mucin - Pitfalls and traps()

In order to demonstrate transglutaminase activity in biological samples immunological as well as glutamine- and amine-donor based assays are commonly used. However, the identification of the transglutaminase reaction product, i. e. the isopeptide cross-linked peptides/proteins or the deamidated prot...

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Detalles Bibliográficos
Autores principales: Arike, Liisa, Hansson, Gunnar C., Recktenwald, Christian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184670/
https://www.ncbi.nlm.nih.gov/pubmed/32222540
http://dx.doi.org/10.1016/j.ab.2020.113668