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The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan

Trained immunity confers a sustained augmented response of innate immune cells to a secondary challenge, via a process dependent on metabolic and transcriptional reprogramming. Because of its previous associations with metabolic and transcriptional memory, as well as the importance of H3 histone lys...

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Detalles Bibliográficos
Autores principales: Keating, Samuel T., Groh, Laszlo, van der Heijden, Charlotte D.C.C., Rodriguez, Hanah, dos Santos, Jéssica C., Fanucchi, Stephanie, Okabe, Jun, Kaipananickal, Harikrishnan, van Puffelen, Jelmer H., Helder, Leonie, Noz, Marlies P., Matzaraki, Vasiliki, Li, Yang, de Bree, L. Charlotte J., Koeken, Valerie A.C.M., Moorlag, Simone J.C.F.M., Mourits, Vera P., Domínguez-Andrés, Jorge, Oosting, Marije, Bulthuis, Elianne P., Koopman, Werner J.H., Mhlanga, Musa, El-Osta, Assam, Joosten, Leo A.B., Netea, Mihai G., Riksen, Niels P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184679/
https://www.ncbi.nlm.nih.gov/pubmed/32320649
http://dx.doi.org/10.1016/j.celrep.2020.107548