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Roles of the HUWE1 ubiquitin ligase in nervous system development, function and disease
Huwe1 is a highly conserved member of the HECT E3 ubiquitin ligase family. Here, we explore the growing importance of Huwe1 in nervous system development, function and disease. We discuss extensive progress made in deciphering how Huwe1 regulates neural progenitor proliferation and differentiation,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184716/ https://www.ncbi.nlm.nih.gov/pubmed/32336296 http://dx.doi.org/10.1186/s13064-020-00143-9 |