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Roles of the HUWE1 ubiquitin ligase in nervous system development, function and disease

Huwe1 is a highly conserved member of the HECT E3 ubiquitin ligase family. Here, we explore the growing importance of Huwe1 in nervous system development, function and disease. We discuss extensive progress made in deciphering how Huwe1 regulates neural progenitor proliferation and differentiation,...

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Detalles Bibliográficos
Autores principales: Giles, Andrew C., Grill, Brock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184716/
https://www.ncbi.nlm.nih.gov/pubmed/32336296
http://dx.doi.org/10.1186/s13064-020-00143-9