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Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

Long non-coding RNAs (lncRNAs) contribute to cardiac (patho)physiology. Aging is the major risk factor for cardiovascular disease with cardiomyocyte apoptosis as one underlying cause. Here, we report the identification of the aging-regulated lncRNA Sarrah (ENSMUST00000140003) that is anti-apoptotic...

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Detalles Bibliográficos
Autores principales: Trembinski, D. Julia, Bink, Diewertje I., Theodorou, Kosta, Sommer, Janina, Fischer, Ariane, van Bergen, Anke, Kuo, Chao-Chung, Costa, Ivan G., Schürmann, Christoph, Leisegang, Matthias S., Brandes, Ralf P., Alekseeva, Tijna, Brill, Boris, Wietelmann, Astrid, Johnson, Christopher N., Spring-Connell, Alexander, Kaulich, Manuel, Werfel, Stanislas, Engelhardt, Stefan, Hirt, Marc N., Yorgan, Kaja, Eschenhagen, Thomas, Kirchhof, Luisa, Hofmann, Patrick, Jaé, Nicolas, Wittig, Ilka, Hamdani, Nazha, Bischof, Corinne, Krishnan, Jaya, Houtkooper, Riekelt H., Dimmeler, Stefanie, Boon, Reinier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184724/
https://www.ncbi.nlm.nih.gov/pubmed/32341350
http://dx.doi.org/10.1038/s41467-020-15995-2