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Oxidative resistance of leukemic stem cells and oxidative damage to hematopoietic stem cells under pro-oxidative therapy

Leukemic stem cells (LSCs) and hematopoietic stem cells (HSCs) are both dependent on the hypoxic bone marrow (BM) microenvironment (also known as the BM niche). There is always fierce competition between the two types of cells, and the former exhibits a greater competitive advantage than the latter...

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Detalles Bibliográficos
Autores principales: Chen, Yongfeng, Liang, Yong, Luo, Xingjing, Hu, Qiongying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184730/
https://www.ncbi.nlm.nih.gov/pubmed/32341354
http://dx.doi.org/10.1038/s41419-020-2488-y