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Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal

Rhabdomyosarcoma (RMS) is the most common soft-tissue pediatric sarcoma. Clinical outcomes for RMS patients with relapsed or metastatic disease remain poor. Treatment options remain limited, presenting an urgent need for novel therapeutic targets. Using a high-throughput siRNA screen against the hum...

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Detalles Bibliográficos
Autores principales: Pham, Thao, Robinson, Kristin, Vleeshouwer-Neumann, Terra, Annis, James E., Chen, Eleanor Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185065/
https://www.ncbi.nlm.nih.gov/pubmed/32363002
http://dx.doi.org/10.18632/oncotarget.27562