Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways

Esophageal carcinoma (EsC) is a clinically challenging neoplastic disease. Genistein, a natural isoflavone product, has anti-tumor properties. Through in vitro and in vivo studies, we found that genistein suppressed EsC cell proliferation in a time- and concentration-dependent manner. In addition, g...

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Detalles Bibliográficos
Autores principales: Gao, Jing, Xia, Rongmu, Chen, Jianbo, Luo, Xianyang, Ke, Chunlin, Ren, Caihong, Li, Jiayi, Mi, Yanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185096/
https://www.ncbi.nlm.nih.gov/pubmed/32276266
http://dx.doi.org/10.18632/aging.103019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185096/
https://www.ncbi.nlm.nih.gov/pubmed/32276266
http://dx.doi.org/10.18632/aging.103019

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