Elevated p38MAPK activity promotes neural stem cell aging

Age-progressive neural stem cell (NSC) dysfunction leads to impaired neurogenesis, cognitive decline and the onset of age-related neurodegenerative pathologies. p38MAPK signalling pathway limits stem cell activity during aging in several tissues. Its role in NSCs remains controversial. In this work,...

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Detalles Bibliográficos
Autores principales: Moreno-Cugnon, Leire, Arrizabalaga, Olatz, Llarena, Irantzu, Matheu, Ander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185101/
https://www.ncbi.nlm.nih.gov/pubmed/32243258
http://dx.doi.org/10.18632/aging.102994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185101/
https://www.ncbi.nlm.nih.gov/pubmed/32243258
http://dx.doi.org/10.18632/aging.102994

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