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Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice

The natural polyamine spermidine and spermine have been reported to ameliorate aging and aging-induced dementia. However, the mechanism is still confused. An aging model, the senescence accelerated mouse-8 (SAMP8), was used in this study. Novel object recognition and the open field test results show...

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Detalles Bibliográficos
Autores principales: Xu, Ting-Ting, Li, Han, Dai, Zhao, Lau, George K., Li, Ben-Yue, Zhu, Wen-Li, Liu, Xiao-Qi, Liu, Hao-Fei, Cai, Wei-Wu, Huang, Shui-Qing, Wang, Qi, Zhang, Shi-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185103/
https://www.ncbi.nlm.nih.gov/pubmed/32268299
http://dx.doi.org/10.18632/aging.103035