Nrf2 deficiency promotes the increasing trend of autophagy during aging in skeletal muscle: a potential mechanism for the development of sarcopenia

This study aims to explore the impact of nuclear factor erythroid 2-related factor 2 (Nrf2) deficiency on skeletal muscle autophagy and the development of sarcopenia. LC3b, P62, Bnip3, Lamp-1, and AMPK protein levels were measured in muscle from young, middle-aged, old Nrf2−/− (knockout, KO) mice an...

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Detalles Bibliográficos
Autores principales: Huang, Dong-Dong, Yan, Xia-Lin, Fan, Sheng-Dong, Chen, Xi-Yi, Yan, Jing-Yi, Dong, Qian-Tong, Chen, Wei-Zhe, Liu, Na-Xin, Chen, Xiao-Lei, Yu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185110/
https://www.ncbi.nlm.nih.gov/pubmed/32244226
http://dx.doi.org/10.18632/aging.102990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185110/
https://www.ncbi.nlm.nih.gov/pubmed/32244226
http://dx.doi.org/10.18632/aging.102990

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