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Inhibition of miR-19a partially reversed the resistance of colorectal cancer to oxaliplatin via PTEN/PI3K/AKT pathway

Oxaliplatin is a platinum-based chemotherapeutic drug that is effective and commonly used in the treatment of colorectal cancer (CRC). However, long-term use of oxaliplatin usually induces significant drug resistance. It is urgent to develop strategies to reverse the oxaliplatin resistance to CRC ce...

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Detalles Bibliográficos
Autores principales: Zhang, Ye, Liu, Xinxin, Zhang, Junying, Xu, Yuanyuan, Shao, Jie, Hu, Yue, Shu, Peng, Cheng, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185119/
https://www.ncbi.nlm.nih.gov/pubmed/32209726
http://dx.doi.org/10.18632/aging.102929