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Klotho antagonizes pulmonary fibrosis through suppressing pulmonary fibroblasts activation, migration, and extracellular matrix production: a therapeutic implication for idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) has been widely accepted as an aging-related fatal lung disease with a therapeutic impasse, largely a consequence of the complex and polygenic gene architecture underlying the molecular pathology of IPF. Here, by conducting an integrative network analysis on the l...

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Detalles Bibliográficos
Autores principales: Huang, Qiqing, Chen, Yan, Shen, Shaoran, Wang, Yuanyuan, Liu, Liya, Wu, Shuangshuang, Xu, Wei, Zhao, Weihong, Lin, Mingyan, Wu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185122/
https://www.ncbi.nlm.nih.gov/pubmed/32244228
http://dx.doi.org/10.18632/aging.102978