Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway

Premature senescence of bone marrow-derived mesenchymal stem cells (BMSC) remains a major concern for their application clinically. Hedgehog signaling has been reported to regulate aging-associated markers and MSC skewed differentiation. Indian Hedgehog (IHH) is a ligand of Hedgehog intracellular pa...

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Detalles Bibliográficos
Autores principales: Al-Azab, Mahmoud, Wang, Bing, Elkhider, Abdalkhalig, Walana, Williams, Li, Weiping, Yuan, Bo, Ye, Yunshan, Tang, Yawei, Almoiliqy, Marwan, Adlat, Salah, Wei, Jing, Zhang, Yan, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185126/
https://www.ncbi.nlm.nih.gov/pubmed/32235006
http://dx.doi.org/10.18632/aging.102958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185126/
https://www.ncbi.nlm.nih.gov/pubmed/32235006
http://dx.doi.org/10.18632/aging.102958

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