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Estradiol-induced senescence of hypothalamic astrocytes contributes to aging-related reproductive function declines in female mice

Hypothalamic astrocytes are important contributors that activate gonadotropin-releasing hormone (GnRH) neurons and promote GnRH/LH (luteinizing hormone) surge. However, the potential roles and mechanisms of astrocytes during the early reproductive decline remain obscure. The current study reported t...

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Detalles Bibliográficos
Autores principales: Dai, Xiaoman, Hong, Luyan, Shen, Hui, Du, Qiang, Ye, Qinyong, Chen, Xiaochun, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185128/
https://www.ncbi.nlm.nih.gov/pubmed/32259796
http://dx.doi.org/10.18632/aging.103008