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Estradiol-induced senescence of hypothalamic astrocytes contributes to aging-related reproductive function declines in female mice
Hypothalamic astrocytes are important contributors that activate gonadotropin-releasing hormone (GnRH) neurons and promote GnRH/LH (luteinizing hormone) surge. However, the potential roles and mechanisms of astrocytes during the early reproductive decline remain obscure. The current study reported t...
Autores principales: | Dai, Xiaoman, Hong, Luyan, Shen, Hui, Du, Qiang, Ye, Qinyong, Chen, Xiaochun, Zhang, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185128/ https://www.ncbi.nlm.nih.gov/pubmed/32259796 http://dx.doi.org/10.18632/aging.103008 |
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