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Leptin acts on mesenchymal stem cells to promote chemoresistance in osteosarcoma cells

Leptin signaling influences osteoblastogenesis and modulates the fate of mesenchymal stem cells (MSCs) during bone and cartilage regeneration. Although MSCs abound in the osteosarcoma (OS) microenvironment, and leptin exhibits pro-tumorigenic properties, leptin’s influence on OS progression and chem...

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Detalles Bibliográficos
Autores principales: Feng, Helin, Zhang, Qianqian, Zhao, Yi, Zhao, Lili, Shan, Baoen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185129/
https://www.ncbi.nlm.nih.gov/pubmed/32289750
http://dx.doi.org/10.18632/aging.103027