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Lower Body Weight in Rats Under Hypobaric Hypoxia Exposure Would Lead to Reduced Right Ventricular Hypertrophy and Increased AMPK Activation

BACKGROUND: Both chronic hypoxia (CH) and long-term chronic intermittent hypoxia (CIH) exposure lead to right ventricular hypertrophy (RVH). Weight loss is an effective intervention to improve cardiac function and energy metabolism in cardiac hypertrophy. Likewise, caloric restriction (CR) also play...

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Detalles Bibliográficos
Autores principales: Flores, Karen, Siques, Patricia, Brito, Julio, Ordenes, Stefany, Arriaza, Karem, Pena, E., León-Velarde, Fabiola, López, Rosario, López de Pablo, Ángel L., Arribas, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185171/
https://www.ncbi.nlm.nih.gov/pubmed/32372974
http://dx.doi.org/10.3389/fphys.2020.00342