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Receptor signaling, transcriptional, and metabolic regulation of T cell exhaustion

Exhaustion cripples T cell effector responses against metastatic cancers and chronic infections alike. There has been considerable interest in understanding the molecular and cellular mechanisms driving T cell exhaustion in human cancers fueled by the success of immunotherapy drugs especially the ch...

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Detalles Bibliográficos
Autor principal: Balkhi, Mumtaz Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185212/
https://www.ncbi.nlm.nih.gov/pubmed/32363117
http://dx.doi.org/10.1080/2162402X.2020.1747349