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Receptor signaling, transcriptional, and metabolic regulation of T cell exhaustion
Exhaustion cripples T cell effector responses against metastatic cancers and chronic infections alike. There has been considerable interest in understanding the molecular and cellular mechanisms driving T cell exhaustion in human cancers fueled by the success of immunotherapy drugs especially the ch...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185212/ https://www.ncbi.nlm.nih.gov/pubmed/32363117 http://dx.doi.org/10.1080/2162402X.2020.1747349 |