Total saponin of Dioscorea collettii attenuates MSU crystal-induced inflammation via inhibiting the activation of the NALP3 inflammasome and caspase-1 in THP-1 macrophages

Total saponins extracted from Dioscorea collettii (TSD), extracts of the Chinese herb Dioscorea, are thought to exhibit therapeutic benefit in gouty arthritis. However, its exact mechanism remains unclear. The current study aimed to elucidate the underlying mechanisms by investigating the effects of...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Zhu, Liran, Duan, Chenfangyuan, Li, Lu, Chen, Guangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185280/
https://www.ncbi.nlm.nih.gov/pubmed/32236574
http://dx.doi.org/10.3892/mmr.2020.11035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185280/
https://www.ncbi.nlm.nih.gov/pubmed/32236574
http://dx.doi.org/10.3892/mmr.2020.11035

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