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CCL11 increases the proportion of CD4(+)CD25(+)Foxp3(+) Treg cells and the production of IL-2 and TGF-β by CD4(+) T cells via the STAT5 signaling pathway
CD4(+) regulatory T (Treg) cells are associated with immune tolerance and antitumor immunosuppression. The aim of the present study was to investigate the role and molecular mechanism of C-C motif chemokine ligand 11 (CCL11) in the regulation of Treg cells from patients with breast cancer (BC) and h...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185287/ https://www.ncbi.nlm.nih.gov/pubmed/32323817 http://dx.doi.org/10.3892/mmr.2020.11049 |