Efficient Construction of a Complete Index for Pan-Genomics Read Alignment

Short-read aligners predominantly use the FM-index, which is easily able to index one or a few human genomes. However, it does not scale well to indexing collections of thousands of genomes. Driving this issue are the two chief components of the index: (1) a rank data structure over the Burrows–Whee...

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Detalles Bibliográficos
Autores principales: Kuhnle, Alan, Mun, Taher, Boucher, Christina, Gagie, Travis, Langmead, Ben, Manzini, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185338/
https://www.ncbi.nlm.nih.gov/pubmed/32181684
http://dx.doi.org/10.1089/cmb.2019.0309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185338/
https://www.ncbi.nlm.nih.gov/pubmed/32181684
http://dx.doi.org/10.1089/cmb.2019.0309

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