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Inhibition of the OAS/RNase L pathway by viruses

The OAS/RNase L system was one of the first characterized interferon effector pathways. It relies on the synthesis, by oligoadenylate synthetases (OAS), of short oligonucleotides that act as second messengers to activate the latent cellular RNase L. Viruses have developed diverse strategies to escap...

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Detalles Bibliográficos
Autores principales: Drappier, Melissa, Michiels, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185432/
https://www.ncbi.nlm.nih.gov/pubmed/26231767
http://dx.doi.org/10.1016/j.coviro.2015.07.002