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Emerging Themes in PDZ Domain Signaling: Structure, Function, and Inhibition
Post-synaptic density-95, disks-large and zonula occludens-1 (PDZ) domains are small globular protein–protein interaction domains widely conserved from yeast to humans. They are composed of ∼90 amino acids and form a classical two α-helical/six β-strand structure. The prototypical ligand is the C-te...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185565/ https://www.ncbi.nlm.nih.gov/pubmed/30712672 http://dx.doi.org/10.1016/bs.ircmb.2018.05.013 |