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The Eukaryotic Translation Initiation Factor 4E (eIF4E) as a Therapeutic Target for Cancer

Cancer cells depend on cap-dependent translation more than normal tissue. This explains the emergence of proteins involved in the cap-dependent translation as targets for potential anticancer drugs. Cap-dependent translation starts when eIF4E binds to mRNA cap domain. This review will present eIF4E&...

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Detalles Bibliográficos
Autores principales: Karaki, Sara, Andrieu, Claudia, Ziouziou, Hajer, Rocchi, Palma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185574/
https://www.ncbi.nlm.nih.gov/pubmed/26572974
http://dx.doi.org/10.1016/bs.apcsb.2015.09.001