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The Eukaryotic Translation Initiation Factor 4E (eIF4E) as a Therapeutic Target for Cancer
Cancer cells depend on cap-dependent translation more than normal tissue. This explains the emergence of proteins involved in the cap-dependent translation as targets for potential anticancer drugs. Cap-dependent translation starts when eIF4E binds to mRNA cap domain. This review will present eIF4E&...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185574/ https://www.ncbi.nlm.nih.gov/pubmed/26572974 http://dx.doi.org/10.1016/bs.apcsb.2015.09.001 |