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The Eukaryotic Translation Initiation Factor 4E (eIF4E) as a Therapeutic Target for Cancer

Cancer cells depend on cap-dependent translation more than normal tissue. This explains the emergence of proteins involved in the cap-dependent translation as targets for potential anticancer drugs. Cap-dependent translation starts when eIF4E binds to mRNA cap domain. This review will present eIF4E&...

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Detalles Bibliográficos
Autores principales:	Karaki, Sara, Andrieu, Claudia, Ziouziou, Hajer, Rocchi, Palma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185574/ https://www.ncbi.nlm.nih.gov/pubmed/26572974 http://dx.doi.org/10.1016/bs.apcsb.2015.09.001

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