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Use of a mouse model to identify a blood biomarker for IFNγ activity in pediatric secondary hemophagocytic lymphohistiocytosis

Life-threatening cytokine release syndromes include primary (p) and secondary (s) forms of hemophagocytic lymphohistiocytosis (HLH). Below detection in healthy individuals, interferon γ (IFNγ) levels are elevated to measurable concentrations in these afflictions suggesting a central role for this cy...

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Detalles Bibliográficos
Autores principales: Buatois, Vanessa, Chatel, Laurence, Cons, Laura, Lory, Sabrina, Richard, Françoise, Guilhot, Florence, Johnson, Zoë, Bracaglia, Claudia, De Benedetti, Fabrizio, de Min, Cristina, Kosco-Vilbois, Marie H., Ferlin, Walter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185816/
https://www.ncbi.nlm.nih.gov/pubmed/27559680
http://dx.doi.org/10.1016/j.trsl.2016.07.023