Co-regulation of the antagonistic RepoMan:Aurora-B pair in proliferating cells

Chromosome segregation during mitosis is antagonistically regulated by the Aurora-B kinase and RepoMan (recruits PP1 onto mitotic chromatin at anaphase)-associated phosphatases PP1/PP2A. Aurora B is overexpressed in many cancers but, surprisingly, this only rarely causes lethal aneuploidy. Here we s...

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Detalles Bibliográficos
Autores principales: Manzione, Maria Giulia, Rombouts, Jan, Steklov, Mikhail, Pasquali, Lorenzo, Sablina, Anna, Gelens, Lendert, Qian, Junbin, Bollen, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185888/
https://www.ncbi.nlm.nih.gov/pubmed/31967936
http://dx.doi.org/10.1091/mbc.E19-12-0698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185888/
https://www.ncbi.nlm.nih.gov/pubmed/31967936
http://dx.doi.org/10.1091/mbc.E19-12-0698

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