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Multivariate analysis reveals activation-primed fibroblast geometric states in engineered 3D tumor microenvironments
Fibroblasts are a heterogeneous group of cells comprising subpopulations that have been found to be activated in the stromal microenvironment that regulates tumor initiation and growth. The underlying mechanisms of such selective activation of fibroblasts are not understood. We propose that the intr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185960/ https://www.ncbi.nlm.nih.gov/pubmed/32023167 http://dx.doi.org/10.1091/mbc.E19-08-0420 |