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Oxysterol-binding protein-related protein 1 variants have opposing cholesterol transport activities from the endolysosomes
OSBPL1 encodes the full-length oxysterol-binding protein-related protein ORP1L, which transports LDL-derived cholesterol at membrane contacts between the late endosomes/lysosomes (LEL) and the endoplasmic reticulum (ER). OSBPL1 also encodes the truncated variant ORP1S that contains only the C-termin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185962/ https://www.ncbi.nlm.nih.gov/pubmed/32023146 http://dx.doi.org/10.1091/mbc.E19-12-0697 |