Cargando…
Oxysterol-binding protein-related protein 1 variants have opposing cholesterol transport activities from the endolysosomes
OSBPL1 encodes the full-length oxysterol-binding protein-related protein ORP1L, which transports LDL-derived cholesterol at membrane contacts between the late endosomes/lysosomes (LEL) and the endoplasmic reticulum (ER). OSBPL1 also encodes the truncated variant ORP1S that contains only the C-termin...
Autores principales: | Zhao, Kexin, Foster, Jason, Ridgway, Neale D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185962/ https://www.ncbi.nlm.nih.gov/pubmed/32023146 http://dx.doi.org/10.1091/mbc.E19-12-0697 |
Ejemplares similares
-
Phosphorylation of a serine/proline-rich motif in oxysterol binding protein-related protein 4L (ORP4L) regulates cholesterol and vimentin binding
por: Pietrangelo, Antonietta, et al.
Publicado: (2019) -
Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis
por: Goto, Asako, et al.
Publicado: (2012) -
A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking
por: Du, Ximing, et al.
Publicado: (2011) -
Regulation of Oxysterol-binding Protein Golgi Localization through Protein Kinase D–mediated Phosphorylation
por: Nhek, Sokha, et al.
Publicado: (2010) -
Oxysterol Binding Protein-dependent Activation of Sphingomyelin Synthesis in the Golgi Apparatus Requires Phosphatidylinositol 4-Kinase IIα
por: Banerji, Sangeeta, et al.
Publicado: (2010)