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Oxysterol-binding protein-related protein 1 variants have opposing cholesterol transport activities from the endolysosomes

OSBPL1 encodes the full-length oxysterol-binding protein-related protein ORP1L, which transports LDL-derived cholesterol at membrane contacts between the late endosomes/lysosomes (LEL) and the endoplasmic reticulum (ER). OSBPL1 also encodes the truncated variant ORP1S that contains only the C-termin...

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Detalles Bibliográficos
Autores principales: Zhao, Kexin, Foster, Jason, Ridgway, Neale D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185962/
https://www.ncbi.nlm.nih.gov/pubmed/32023146
http://dx.doi.org/10.1091/mbc.E19-12-0697

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