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The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy

DNA-damaging chemotherapeutics are widely used in cancer treatments, but for solid tumors they often leave a residual tumor-cell population. Here we investigated how cellular states might affect the response of individual cells in a clonal population to cisplatin, a DNA-damaging chemotherapeutic age...

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Detalles Bibliográficos
Autores principales: Granada, Adrián E., Jiménez, Alba, Stewart-Ornstein, Jacob, Blüthgen, Nils, Reber, Simone, Jambhekar, Ashwini, Lahav, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185964/
https://www.ncbi.nlm.nih.gov/pubmed/32049575
http://dx.doi.org/10.1091/mbc.E19-09-0515