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The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy
DNA-damaging chemotherapeutics are widely used in cancer treatments, but for solid tumors they often leave a residual tumor-cell population. Here we investigated how cellular states might affect the response of individual cells in a clonal population to cisplatin, a DNA-damaging chemotherapeutic age...
Autores principales: | Granada, Adrián E., Jiménez, Alba, Stewart-Ornstein, Jacob, Blüthgen, Nils, Reber, Simone, Jambhekar, Ashwini, Lahav, Galit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185964/ https://www.ncbi.nlm.nih.gov/pubmed/32049575 http://dx.doi.org/10.1091/mbc.E19-09-0515 |
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