The Rho-guanine nucleotide exchange factor Solo decelerates collective cell migration by modulating the Rho-ROCK pathway and keratin networks

Collective cell migration plays crucial roles in tissue remodeling, wound healing, and cancer cell invasion. However, its underlying mechanism remains unknown. Previously, we showed that the RhoA-targeting guanine nucleotide exchange factor Solo (ARHGEF40) is required for tensile force–induced RhoA...

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Detalles Bibliográficos
Autores principales: Isozaki, Yusuke, Sakai, Kouki, Kohiro, Kenta, Kagoshima, Katsuhiko, Iwamura, Yuma, Sato, Hironori, Rindner, Daniel, Fujiwara, Sachiko, Yamashita, Kazunari, Mizuno, Kensaku, Ohashi, Kazumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185966/
https://www.ncbi.nlm.nih.gov/pubmed/32049581
http://dx.doi.org/10.1091/mbc.E19-07-0357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185966/
https://www.ncbi.nlm.nih.gov/pubmed/32049581
http://dx.doi.org/10.1091/mbc.E19-07-0357

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