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The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A

The heterotetrameric adaptor protein complex 4 (AP-4) is a component of a protein coat associated with the trans-Golgi network (TGN). Mutations in AP-4 subunits cause a complicated form of autosomal-recessive hereditary spastic paraplegia termed AP–4-deficiency syndrome. Recent studies showed that A...

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Detalles Bibliográficos
Autores principales: Mattera, Rafael, Williamson, Chad D., Ren, Xuefeng, Bonifacino, Juan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185972/
https://www.ncbi.nlm.nih.gov/pubmed/32073997
http://dx.doi.org/10.1091/mbc.E19-11-0658