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Preserving genome integrity in human cells via DNA double-strand break repair

The efficient maintenance of genome integrity in the face of cellular stress is vital to protect against human diseases such as cancer. DNA replication, chromatin dynamics, cellular signaling, nuclear architecture, cell cycle checkpoints, and other cellular activities contribute to the delicate spat...

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Detalles Bibliográficos
Autores principales: Jensen, Ryan B., Rothenberg, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185975/
https://www.ncbi.nlm.nih.gov/pubmed/32286930
http://dx.doi.org/10.1091/mbc.E18-10-0668