Effects of CYP3A5 Polymorphisms on Efficacy and Safety of Tacrolimus Therapy in Patients with Idiopathic Membranous Nephropathy

BACKGROUND: Tacrolimus (TAC) is beneficial for patients with idiopathic membranous nephropathy (IMN). It has a narrow therapeutic concentration range and many factors influence TAC blood concentration. CYP3A5 is the most important enzyme in TAC metabolism. The aim of this study was to analyze the ef...

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Detalles Bibliográficos
Autores principales: Zhang, Chengning, Duan, Suyan, Guo, Miao, Yuan, Yanggang, Huang, Zhimin, Zhu, Jingfeng, Sun, Bin, Zhang, Bo, Xing, Changying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186213/
https://www.ncbi.nlm.nih.gov/pubmed/32368128
http://dx.doi.org/10.2147/PGPM.S247892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186213/
https://www.ncbi.nlm.nih.gov/pubmed/32368128
http://dx.doi.org/10.2147/PGPM.S247892

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