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Applying MAPPs Assays to Assess Drug Immunogenicity

Immunogenicity against biotherapeutic proteins (BPs) and the potential outcome for the patient are difficult to predict. In vitro assays that can help to assess the immunogenic potential of BPs are not yet used routinely during drug development. MAPPs (MHC-associated peptide proteomics) is one of th...

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Detalles Bibliográficos
Autor principal: Karle, Anette C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186346/
https://www.ncbi.nlm.nih.gov/pubmed/32373128
http://dx.doi.org/10.3389/fimmu.2020.00698