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Applying MAPPs Assays to Assess Drug Immunogenicity
Immunogenicity against biotherapeutic proteins (BPs) and the potential outcome for the patient are difficult to predict. In vitro assays that can help to assess the immunogenic potential of BPs are not yet used routinely during drug development. MAPPs (MHC-associated peptide proteomics) is one of th...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186346/ https://www.ncbi.nlm.nih.gov/pubmed/32373128 http://dx.doi.org/10.3389/fimmu.2020.00698 |