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LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase

Neuroblastoma is an aggressive pediatric malignancy of the neural crest with suboptimal cure rates and a striking predilection for widespread metastases, underscoring the need to identify novel therapeutic vulnerabilities. We recently identified the RNA binding protein LIN28B as a driver in high-ris...

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Detalles Bibliográficos
Autores principales: Chen, Dongdong, Cox, Julie, Annam, Jayabhargav, Weingart, Melanie, Essien, Grace, Rathi, Komal S., Rokita, Jo Lynne, Khurana, Priya, Cuya, Selma M., Bosse, Kristopher R., Pilgrim, Adeiye, Li, Daisy, Shields, Cara, Laur, Oskar, Maris, John M., Schnepp, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186370/
https://www.ncbi.nlm.nih.gov/pubmed/32339949
http://dx.doi.org/10.1016/j.neo.2020.04.001