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Activation of PXR by Alpinetin Contributes to Abrogate Chemically Induced Inflammatory Bowel Disease

Alpinetin is a naturally occurring flavonoid from the ginger plants. We previously reported the identification of alpinetin as a ligand of human pregnane X receptor (hPXR). The current study investigated the role of alpinetin as a putative PXR activator in ameliorating chemically induced inflammator...

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Detalles Bibliográficos
Autores principales: Yu, Zhilun, Yue, Bei, Ding, Lili, Luo, Xiaoping, Ren, Yijing, Zhang, Jingjing, Mani, Sridhar, Wang, Zhengtao, Dou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186371/
https://www.ncbi.nlm.nih.gov/pubmed/32372959
http://dx.doi.org/10.3389/fphar.2020.00474