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Modulation on Glutamic Pathway of Frontal-Striatum-Thalamus by rs11146020 and rs3813296 Gene Polymorphism in First-Episode Negative Schizophrenia

OBJECTIVES: The frontal-striatum-thalamus pathway is important in the glutamic neural circuit. The hypofunction of GRIN1 and GRIA2 subunits from glutamic receptors has been hypothesized as the primary process in the etiology of schizophrenia. Identified gene polymorphism involved in the pathogenesis...

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Detalles Bibliográficos
Autores principales: Cai, Suping, Lv, Yahui, Huang, Kexin, Zhang, Wei, Wang, Qiang, Huang, Liyu, Wang, Jijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186427/
https://www.ncbi.nlm.nih.gov/pubmed/32372910
http://dx.doi.org/10.3389/fnins.2020.00351